Adaptogenic Mushrooms – Part 2

Discovering Adaptogenic Mushrooms – Part 2

This isn't a marketing page. This is your space to understand—with clarity, without fluff. You've probably heard of adaptogens, functional mushrooms, or nootropics. Maybe you're curious. Maybe you're skeptical. Either way, you deserve transparency. And real answers. This Wiki explains what's in our formulas, where the ingredients come from, why we use them, and how they can help you feel like yourself again. No buzzwords. No empty promises. Just simple, clear, science-backed explanations.

— What are functional mushrooms?

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Functional mushrooms aren't magic—but used properly, they can come close.

These mushrooms have been used for centuries in traditional medicines to support energy, immunity, focus, and calmness. Today, modern research confirms what many already knew: certain mushrooms can help the body adapt, recover, and regulate itself.

At Santa Mood, we use functional mushrooms not because they're trendy—but because they work.

And combined with adaptogens, vitamins and active plants, their effects become more targeted, more regular, and more concrete.

— Cordyceps

What is Cordyceps?

Cordyceps (most commonly Cordyceps militaris or Cordyceps sinensis) is a parasitic fungus prized in traditional Chinese medicine for its remarkable ability to increase energy, support immunity, and improve endurance. Modern research attributes these effects to unique bioactive compounds—including cordycepin, polysaccharides, and sterols—that interact with the body's metabolic and immune pathways to promote vitality and resilience.

+ Health benefits

Improved energy and stamina

Cordyceps increases the production of adenosine triphosphate (ATP), the main energy source of cells, leading to better oxygen utilization and improved physical performance in both athletes and the elderly.

Immune system support

The polysaccharides present in cordyceps stimulate macrophage activity and balance cytokine production, helping the body effectively defend against pathogens.

Antioxidant and anti-inflammatory effects

Cordyceps is rich in antioxidants that neutralize free radicals and reduce inflammatory markers, potentially protecting against chronic diseases.

Protection of the kidneys and liver

Animal studies suggest that cordyceps extracts may support kidney function and protect liver cells from toxin-induced damage through anti-fibrotic and hepatoprotective actions.

Blood sugar regulation

Cordyceps may improve insulin sensitivity and help maintain healthy blood glucose levels, making it a promising supplement for metabolic health.

Anti-aging and longevity

Preclinical research indicates that cordycepin and other cordyceps compounds may modulate pathways related to cellular aging, providing potential neuroprotective and anti-aging benefits.

- Possible side effects and precautions

Blood thinning

Cordyceps may exert mild anticoagulant effects; people taking anticoagulant medications should consult a healthcare professional before use.

Gastrointestinal discomfort

High doses may cause digestive disturbances, such as nausea or diarrhea, especially when first used.

Interaction with immunosuppressants

Because cordyceps modulates immune activity, it may interfere with immunosuppressive therapies; medical consultation is recommended for patients who have undergone a transplant or are taking such medications.

Pregnancy and breastfeeding

Safety data are insufficient for these populations; avoid use except under professional supervision.

Scientific research

ATP and physical performance

Immunomodulatory polysaccharides

Antioxidant and anti-inflammatory actions

Metabolic and renal benefits

Anti-aging and neuroprotection

— Lion's Mane

What is Lion's Mane?

Lion's Mane, known as Yamabushitake in Japan, is a white, waterfall-shaped, spiky mushroom prized in traditional Chinese medicine and Japanese Kampo for its cognitive and nerve-supporting benefits. Modern research attributes these effects to unique compounds—erenacines and hericenones—that stimulate neurotrophic activity and support neuronal health.

+ Main benefits

Neurotrophic stimulation

Lion's Mane contains hericenones (in the fruit body) and erenacines (in the mycelium) which promote the synthesis of nerve growth factor (NGF), a protein essential for the survival, maintenance and regeneration of neurons.

Cognitive enhancement

A double-blind trial in older adults with mild cognitive impairment found that 3 g/day of Lion's Mane powder for 16 weeks significantly improved Mental State Examination (MMSE) scores compared to placebo, with effects reversing after treatment discontinuation.

Reduction in mood and anxiety

In a four-week study, daily intake of Lion's Mane biscuits resulted in significant reductions in depression and anxiety scores (CES-D, ICI) compared to placebo, suggesting psychotropic potential.

Neuroprotective effects

In cellular and animal models, Lion's Mane extract reduced oxidative stress, inhibited neuronal apoptosis, and improved motor deficits via ERK-CREB signaling pathways.

Immune modulation

Lion's Mane protein extracts enhanced macrophage phagocytosis, NK cell activity, and SIgA secretion in the intestine, indicating potent immunomodulatory properties.

Antioxidant and anti-inflammatory

Rich in polysaccharides and phenolic compounds, Lion's Mane exhibits strong free radical scavenging activity and reduces pro-inflammatory cytokines in preclinical studies.

- Safety and precautions

Blood scarring

May slow clotting; use caution if taking blood thinners (aspirin, warfarin) to avoid increased risk of bruising and bleeding.

Allergies and gastrointestinal disorders

Rare reports of nausea, rash, or diarrhea; discontinue use if adverse symptoms occur.

Pregnancy and breastfeeding

Insufficient data - avoid use until further human safety studies become available.

Scientific research

Mori K. et al. (2009) — Improvement of cognitive functions by oral intake of Hericium erinaceus in elderly Japanese people: a double-blind, placebo-controlled clinical trial.

Mori K. et al. (2008) — Nerve growth factor-inducing activity of Hericium erinaceus in human astrocytoma 1321N1 cells.

Nagano M. et al. (2010) — Reduction of depression and anxiety by taking Hericium erinaceus for 4 weeks.

Chen DL et al. (2017) — Immunomodulatory activities of a fungal protein extracted from Hericium erinaceus in regulating intestinal microbiota.

Wu CH et al. (2024) — Hericium erinaceus: Comprehensive review of its potential in the prevention and treatment of neurodegenerative diseases.

WebMD — Lion's Mane Mushroom: Benefits, Side Effects, and More.

Peng Q. et al. (2023) — Acute and chronic effects of Lion's Mane mushroom on cognitive function and mood in healthy young adults: a randomized clinical trial.

Zhou X. et al. (2023) — Neurotrophic and neuroprotective effects of Hericium erinaceus: Mechanistic insights and clinical implications.

Healthline — 9 Health Benefits of Lion's Mane Mushroom.

Buzzelli C. et al. (2017) — Immunomodulatory effects of polysaccharides derived from Hericium erinaceus stimulating intestinal immunity.

— Maitake

What is Maitake?

Maitake , also known as "hen of the woods," is a polypore mushroom native to the forests of Japan, China, and North America. Celebrated in traditional Eastern medicine, it has attracted the attention of modern researchers due to its potential health benefits, including immune support, blood sugar regulation, antioxidant properties, and cardiovascular health.

+ Main benefits

Immune system support

Maitake contains beta-glucans, particularly the D fraction, which have been shown to stimulate the immune system by activating macrophages and natural killer (NK) cells.

Blood sugar regulation

Studies suggest that Maitake extracts may help reduce blood glucose levels and improve insulin sensitivity, making it a potential supplement in the management of type 2 diabetes.

Antioxidant properties

Rich in phenolic compounds and flavonoids, Maitake has significant antioxidant activity, helping to combat oxidative stress and protect cellular health.

Anti-inflammatory effects

Compounds isolated from Maitake have demonstrated anti-inflammatory properties, which may help reduce inflammation-related conditions.

Cardiovascular health

Research indicates that Maitake may contribute to cardiovascular health by reducing blood pressure and cholesterol levels.

- Safety and precautions

General security

Maitake is generally considered safe when consumed as part of the diet or as a supplement.

Possible side effects

Some people may experience allergic reactions or digestive discomfort.

Pregnancy and breastfeeding

Due to limited research, pregnant or breastfeeding women are advised to consult a healthcare professional before using Maitake.

Drug interactions

Maitake may interact with hypoglycemic medications; monitoring is recommended for people taking such medications.

Scientific research

Immunomodulatory effects of Grifola frondosa polysaccharides. This study shows that Maitake polysaccharides stimulate the activity of macrophages and natural killer cells, thereby enhancing the immune response.

Antitumor activity of Grifola frondosa fraction D. A review of clinical and preclinical data on the anticancer potential of Maitake fraction D.

Hypoglycemic effects of Grifola frondosa in diabetic models. This research shows that Maitake extracts help lower blood glucose levels and improve insulin sensitivity.

Antioxidant and Anti-Inflammatory Properties of Grifola Frondosa. A comprehensive review highlighting the antioxidant and anti-inflammatory benefits of Maitake through various studies.

Cardiovascular benefits of Grifola frondosa.

This article explains how Maitake can help lower cholesterol, decrease triglycerides, and regulate blood pressure.

— Frequently Asked Questions

Store in a cool, dry place away from direct light. After opening, it is recommended to refrigerate the gummies.

Effects can appear after several weeks or even months of regular use, depending on what you're looking to improve—whether it's cognitive function, physical endurance, or immunity.

Taking functional mushrooms is not recommended without prior medical advice, as the safety of some mushrooms during pregnancy or breastfeeding has not yet been adequately studied.

In most cases, functional mushrooms are well tolerated. However, if you suffer from a chronic illness, it's best to seek advice from a healthcare professional to avoid possible interactions with your medications.